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2010-2012
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Portfolio News
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New Leaf News
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 Archive
Newly Formed Durata Therapeutics Acquires
Pfizer’s Vicuron Subsidiary
December 21, 2009
ISTA Pharmaceuticals Submits Supplemental New
Drug Application to the FDA for Once-Daily XiDay™
December 17, 2009
Auxilium Announces Top Line Phase IIb
XIAFLEX™ Peyronie's Results
December 16, 2009
Roche Licenses First-in-Class Treatments for
Chronic Pain to Afferent Pharmaceuticals; Afferent Secures $23 Million in Series
A Financing
December 16, 2009
Transcept Pharmaceuticals Receives Notice of
Allowance for Second U.S. Patent Application Covering Intermezzo®
December 14, 2009
WuXi PharmaTech Selects Labcyte POD™ 810
Platform for High-Throughput Screening
December 07, 2009
Affymax Announces Close of Common Stock
Offering and Exercise of Underwriters' Overallotment Option
November 24, 2009
WorldHeart Signs Agreements for
Next-Generation Minimally Invasive Blood Pump
November 17, 2009
NeuroStar TMS Therapy® Receives Prestigious
Popular Science Award
November 12, 2009
3M Licenses Vaccine Adjuvants to VaxInnate
November 9, 2009
Concert Pharmaceuticals Initiates Phase 1b
Clinical Trial of CTP-518, Protease Inhibitor for Treatment of HIV
November 9, 2009
Transcept Pharmaceuticals Receives Notice of
Allowance for U.S. Patent Application on Intermezzo®
November 4, 2009
Affymax and Takeda Announce Preliminary Phase 2 Data Demonstrated That
Hematide™ Increased Hemoglobin in Dialysis Patients
October 30, 2009
Epocrates Celebrates 10 Years of Innovation
October 29, 2009
FDA Clears Interlace Medical’s MyoSure™
Hysteroscopic Tissue Removal System for The Treatment of Submucosal Fibroids
October 28th, 2009
Ligand to Acquire Metabasis for Cash and Contingent Value Rights
October 27, 2009
NxStage® Reports Significant Interim FREEDOM Study Results
October 27, 2009
Synageva Biopharma Announces
Completion of $45 Million Financing with New $12 Million Investment, Addition of
New Leaf Venture Partners to Investor Group, and Expansion of Senior Leadership
Team
October 20, 2009
Prometheus Awarded Patent Related to Genetic
Testing for Inflammatory Bowel Disease
October 20, 2009
WorldHeart Receives IRB Approval at First Center in the Levacor™ VAD BTT Clinical Trial Center On-Site Training Completed
October 15, 2009
Prometheus Launches ProOncDx Cancer Diagnostics
October 15, 2009
Relypsa Initiates Phase 2b Clinical Trial of
RLY5016 for the Prevention of Hyperkalemia in Heart Failure Patients
October 7, 2009
Direct Flow Medical Presents Twelve Month
Clinical Results with their Percutaneous Aortic Valve System at TCT
October 5, 2009
Boston Business Journal Names NxStage® Medical
Third Fastest Growing Company in Massachusetts
October 1, 2009
Cyberonics Announces Epilepsy Technology
Collaborations
October 1, 2009
Labcyte Signs Bioscreen Instruments as
Exclusive Distributor in India
September 23, 2009
Intarcia Therapeutics, Inc. Commences
Enrollment of ITCA 650 Phase 2 Study in Type 2 Diabetes
September 17, 2009
U.S. Food and Drug Administration's Arthritis
Advisory Committee Votes Unanimously 12-0 to Recommend Approval of XIAFLEX™ for
Dupuytren's Contracture
September 16, 2009
Concert Pharmaceuticals Presents
Clinical Results Demonstrating Reduced Drug-Drug Interactions with a
Deuterium-Modified Compound
September 14, 2009
NxStage® Announces Streamline® Blood Tubing
Set Supply Agreement Between Medisystems® and Reliant Renal Care
September 14, 2009
Affymax Provides Phase 3 Program
Update for Investigational Drug, Hematide™, to Treat Anemia in Chronic Renal
Failure
September 9, 2009
Prometheus Announces Co-Pay Assistance Savings
Program For LOTRONEX® (Alosteron Hcl) Tablets
September 9, 2009
ISTA Pharmaceuticals' Bepreve™
Receives FDA Approval for the Treatment of Ocular Itching Due to
Allergies
September 8, 2009
ISTA Pharmaceuticals Announces Preliminary
Results of T-Pred Studies
September 8, 2009
XIAFLEX™ CORD I Study Published in New
England Journal of Medicine
September 2, 2009
Abbott to Acquire Visiogen, Expanding Vision Care Portfolio
September 2, 2009
New Leaf Venture Partners Leads $30 Million Financing in Neuronetics
September 2, 2009
Tioga Pharmaceuticals, Inc. and Ono
Pharmaceutical Co. Announce Agreement to Develop and Commercialize Asimadoline
in Japan
September 1, 2009
Aureon Laboratories Announces Appointment of
New CEO
August 25, 2009
ISTA Pharmaceuticals Announces Positive
Preliminary Phase 3 Clinical Results to Support sNDA Filing for
Once-Daily Xibrom™ 0.09%
August 25, 2009
WorldHeart Receives US Clinical Study Approval for the Levacor™ VAD
August 20, 2009
Labcyte Awarded Second Japanese Patent
August 18, 2009
XDx Completes $14.4 Million Series G
Financing XDx Poised to Achieve Break-Even in 2010
August 5, 2009
Auxilium Pharmaceuticals, Inc. Secures $30
Million Revolving Credit Line With Silicon Valley Bank
August 5, 2009
Dr. Nathaniel Brown Joins Presidio
Pharmaceuticals, Inc. as Senior Vice President of Clinical
Development
August 5, 2009
Purdue Pharmaceutical Products L.P. and
Transcept Pharmaceuticals, Inc. Sign Exclusive Agreement to
Commercialize Intermezzo® in the United States
August 2, 2009
U.S. Food and Drug Administration's
Arthritis Advisory Committee Confirms Date to Review XIAFLEX™
for the Treatment of Dupuytren's Contracture
July 31, 2009
Affymax Announces Data Monitoring Committee
Review of Phase 3 Hematide Program
July 20, 2009
Presidio Pharmaceuticals Inc. Raises $27 Million in Additional Financing
July 9, 2009
Presidio Pharmaceuticals, Inc. selects PPI-461 as a Clinical Candidate in their Hepatitis C Virus NS5A Program
July 7, 2009
Prometheus Launches MyCeliacID™, The First Do It Yourself, Saliva-Based Genetic Test Dedicated To Celiac Disease June 29, 2009
U.S. Food and Drug Administration's Arthritis
Advisory Committee Sets Tentative Date to Review XIAFLEX™
for the Treatment of Dupuytren's Contracture
June 18, 2009
Transcept Pharmaceuticals Announces
Expected FDA Extension of Regulatory Review Period for
Intermezzo®
June 11, 2009
Metabasis Therapeutics
Announces That Its Collaborator Merck & Co., Inc. Has
Selected a Lead AMPK Activator for Late Preclinical
Development and Has Agreed to Make a One-Time Payment for
All Remaining Financial Obligations
June 10, 2009
Metabasis Therapeutics
Receives a Development Event Payment from Roche and
Notification That Roche Plans to Advance MB11362 into
Development for the Treatment of Hepatitis C
June 5, 2009
Concert
Pharmaceuticals and GlaxoSmithKline Form Alliance to Develop
Novel Deuterium Modified Drugs
June 2, 2009
Prometheus Announces New
Findings Regarding Patients at Risk for Celiac Disease at
DDW
June 2, 2009
NxStage Extends Supply
Agreement with B. Braun Medical Inc. to Include
Streamline(R) Technology
June 1, 2009
Affymax® Reports Phase 2 Clinical
Trial Data Supporting Hemoglobin Increases with Once-Per-Month Hematide™ Regardless of Patient
Baseline Renal Function
May 26, 2009
Transcept Pharmaceuticals
Presents Data from Studies of Two Product Candidates at
Annual Meeting of the American Psychiatric Association
May 21, 2009
NxStage Announces
Strategic Business Alliance with Asahi Kasei Kuraray Medical
May 18, 2009
VaxInnate Corporation
Closes $30 Million Round of Financing; Wellcome Trust Leads
Round
May 6, 2009
XIAFLEX™ for the
Treatment of Dupuytren's Contracture Receives Priority Review
from the U.S. Food and Drug Administration
April 28, 2009
Prometheus and
Rosetta Genomics Announce License and Collaboration
Agreement
April 13, 2009
Prometheus
Highlights Record Performance in 2008
March 24, 2009
NxStage
Announces Credit Facility Amendment
March 16, 2009
Prometheus
Receives New York State Approval for Prometheus® IBS
Diagnostic, First Blood Test for Irritable Bowel Syndrome
March 16, 2009
Auxilium Submits
Biologics License Application for XIAFLEX™ for the Treatment of Dupuytren's Contracture to the U.S. Food and Drug
Administration
March 02, 2009
IlluminOss Medical Receives ISO 13485 Certification
February 20, 2009
IlluminOss
Announces First Human Case Utilizing Its Innovative
Photodynamic Bone Stabilization System Technology
February 19, 2009
Affymax Announces
$42 Million Private Placement
February 17, 2009
Auxilium Pharmaceuticals, Inc. Completes
Enrollment in Phase IIb Clinical Trial of XIAFLEX™
in Peyronie's Disease
February 2, 2009
Novacea Stockholders Approve Merger With Transcept
January 27, 2009
ISTA
Pharmaceuticals Announces Positive Results for Phase IIb
Study of Ecabet Sodium
January 22, 2009
WorldHeart Submits IDE Application for a
Pivotal Bridge-to-Transplant Study of the Levacor™ VAD
January 8, 2009
Auxilium Pharmaceuticals, Inc. and Pfizer Enter Agreement to
Develop and Commercialize XIAFLEX™ in Europe
December 17, 2008
Transcept
Announces FDA Acceptance for Review of New Drug Application
for Intermezzo®
December 16, 2008
Epocrates Offers International Market Research Panel
November 20, 2008
Affymax Announces Another Favorable Data Monitoring
Committee Review of Phase 3 Hematide Program
November 20, 2008
Epocrates Survey Identifies Trends in Online Resource Use
Among Physicians
November 18, 2008
Affymax Completes Enrollment in Phase 3 Program
for Hematide in Chronic Renal Failure with Completion of
Enrollment in EMERALD 2, the Final of Four Phase 3 Clinical
Trials of Hematide™
November 17, 2008
ISTA Pharmaceuticals Ranked Number Twelve in Deloitte's
Technology Fast 500 Program for Fastest Growing Companies in
North America
November 13, 2008
ISTA Pharmaceuticals Files New Drug
Application with U.S. FDA for Bepreve™
November 13, 2008
Fifty Thousand Physicians Choose Epocrates iPhone App
November 6, 2008
Affymax Announces New Data
Presented on the Long-Term Safety and Effectiveness of
Hematide™ to Treat Anemia in Chronic Renal Failure
Patients with Monthly Dosing
November 6, 2008
Affymax Completes
Enrollment in PEARL 2, the Second of Four Phase 3 Clinical
Trials of Hematide to Treat Anemia in Chronic Renal Failure
Patients
November 3, 2008
Transcept Submits NDA for
Intermezzo® for Treatment of Middle-of-the-Night Awakenings
October 1, 2008
ISTA Pharmaceuticals
Receives $65 Million Funding Commitment
September 26, 2008
Concert
Pharmaceuticals Presents Preclinical Results Supporting
Co-Administration of CTP-347 and Tamoxifen
September 25, 2008
One Million Epocrates MobileCME Courses Completed
September 25, 2008
Oriel Therapeutics Appoints Richard Fuller as Chief
Executive Officer
September 23, 2008
Auxilium Pharmaceuticals,
Inc. Announces Initiation of XIAFLEX™ Phase IIb Study for
Peyronie's Disease
September 17, 2008
Apple iPhone Becomes a Patient Safety Device with Epocrates
September 15, 2008
Intarcia Therapeutics, Inc. Announces Appointment of Kenneth
Luskey, M.D. as Vice President, Clinical Research
September 9, 2008
Novacea, Inc.
and Transcept Pharmaceuticals, Inc. Sign Merger Agreement
September 2, 2008
Patent Issued Related to Prometheus Proprietary Test; CBir1 Antigen Test Included in Diagnostic for Inflammatory Bowel Disease
August 21, 2008
Affymax Announces
Favorable Data Monitoring Committee Review of Phase 3
Hematide Program
August 7, 2008
WorldHeart Closes US$30
Million in Financing
August 1, 2008
Angiotech To
Establish Separate Operating And Royalty Businesses
July 7, 2008
Pearl Therapeutics Closes $18 Million Financing
July 2, 2008
Tioga Pharmaceuticals’ Asimadoline Demonstrates Positive Results
in a Phase 2b Clinical Trial for the Treatment of Irritable Bowel Syndrome
May 20, 2008
Aureon
Laboratories Introduces Prostate Px® , First Biopsy-Based
Test to Predict Prostate Cancer Disease Progression and
Recurrence
May 19, 2008
Affymax and Takeda Announce Long-Term Hematide Safety and
Effectiveness Data from Phase 2 Clinical Trials in Chronic
Kidney Disease Patients with Anemia
May 12, 2008
NxStage Announces Supply
Agreement With Kawasumi Laboratories for Blood Tubing Sets
May 7, 2008
ISTA Pharmaceuticals
Announces New Phase III Clinical Findings to Support Bepreve
NDA Filing
April 30, 2008
CoNCERT Pharmaceuticals Raises
$37 Million in Series C Financing
April 30, 2008
Stromedix Raises $25 Million Series B for Fibrosis Programs,
Begins Clinical Trial
April 21, 2008
IlluminOss Medical Completes $11 Million Series B Financing
April 18, 2008
Metabasis Therapeutics Raises Approximately $10 Million
Through a Warrant Exchange and Concurrent Private Placement
April 16, 2008
Apple Announces iPhone 2.0 Software Beta
March 6, 2008
Artisan Pharma's Lead Product, ART-123, Approved in Japan
February 22, 2008
ISTA Pharmaceuticals Announces Physician-Sponsored Clinical
Study of Xibrom™ Combination
Therapy with Lucentis®
February 22, 2008
SGX Initiates Phase I
Trials for SGX523
January 16, 2008
Epocrates Inc. Announces Strategic Investment by
Goldman Sachs
January 7, 2008
NxStage Medical Announces Needle Supply Agreement with
DaVita
January 7, 2008
Aspreva's Plan of
Arrangement with Galenica Completed
January 3, 2008
ISTA Pharmaceuticals
Submits New Drug Application for Xibrom™ QD (once-daily)
December 20, 2007
Kalypsys Initiates
Phase IIa Clinical Trial of Topical iNOS Inhibitor
December 18, 2007
Auxilium
Pharmaceuticals, Inc. Completes Enrollment in Two Phase III
Clinical Trials of XIAFLEX™ for Dupuytren's Contracture
December 17, 2007
SGX Pharmaceuticals
Submits Investigational New Drug Application for SGX523, a
Highly Potent, Selective, Orally Bioavailable cMET Inhibitor
December 3, 2007
Prometheus Licenses
Colal-Pred® From Alizyme
November 29, 2007
NxStage Medical
Establishes $50 Million Credit Facility with a Group of
Lenders Led by Merrill Lynch Capital
November 21, 2007
SGX Pharmaceuticals
Announces $25 Million Private Placement
November 20, 2007
Prescription for
Success: Epocrates for BlackBerry -
Popular Medical Software Now Available for BlackBerry
Smartphones
November 14, 2007
BioRelix and Dalton
Medicinal Chemistry Sign Research Agreement to Capitalize on
RiboSwitch Technology
November 13, 2007
ISTA Pharmaceuticals
Presents Results from Two Phase III Clinical Trials of
Xibrom™ QD (Once-daily) Formulation at the American
Academy of Ophthalmology Annual Meeting
November 12, 2007
Prometheus Laboratories
Inc. to Acquire GlaxoSmithKline (GSK) Bowel Drug
November 7, 2007
Affymax®
Announces Hematide™ Successfully Restores Hemoglobin in
Patients with Pure Red Cell Aplasia (PRCA)
November 5, 2007
Relypsa formed with $33
Million Series A Funding to discover and develop polymeric
drugs.
October 29, 2007
GlaxoSmithKline
(GSK) and Tolerx, Inc. Form Collaboration Worth Up to $700
Million
October 23, 2007
Gary Shearman, Ph.D.
Joins Board of Artisan Pharma, Inc.
October 23, 2007
Aspreva to be Acquired
by Galenica For US$915 Million
October 17, 2007
Aureon Laboratories to
Collaborate with UCSF on Research Study to Construct
Predictive Models for GM-CSF Treatment Response in Patients
with Prostate Cancer
October 15, 2007
Affymax Doses First
Patient in the Phase 3 Clinical Program of Hematide™ to
Treat Anemia in Chronic Renal Failure Patients
October 11, 2007
NxStage Medical
Completes Acquisition of Medisystems
October 1, 2007
Spiration,
Inc. Announces First Patient Enrollment in U.S. Pivotal
Trial of Minimally Invasive Treatment for Severe Emphysema
September 26, 2007
ISTA Pharmaceuticals
Expands Its Pipeline in Allergy Treatments
September 26, 2007
Pearl Therapeutics
Raises $15.5 Million in Private Financing
September 6, 2007
ISTA Pharmaceuticals Completes $36.75 Million
Private Financing
June 29, 2007
TransOral Pharmaceuticals, Inc. Changes Name to Transcept
Pharmaceuticals, Inc.
June 22, 2007
BioRelix Announces $25.75 Million Series A
June 11, 2007
Auxilium Pharmaceuticals
Announces Sale of Common Stock
June 8, 2007
Amgen to Acquire Ilypsa, a Private San Francisco Bay Area
Biotechnology Company Focused on Kidney Disease Care
June 4, 2007
NxStage® Medical Announces Agreement to Acquire Medisystems Corporation
and Certain Affiliated Entities
June 4, 2007
TIBCO to Acquire Spotfire
May 1, 2007
Intarcia Raises $50 Million in a Series BB Financing
March 19, 2007
New Leaf Venture Partners and TPG Growth Co-Lead $20 Million
Series B Financing in ProteoGenix
March 14, 2007
TransOral Pharmaceuticals
Raises $40 Million in Series D Financing
March 6, 2007
Adeza to Be Acquired by Cytyc for $24 Per Share
February 12, 2007
Cerexa to be Acquired by
Forest Laboratories for $480 Million Plus Potential $100 Million
Milestone Payment
December 14, 2006
Concert Pharmaceuticals
Raises $48.5 Million in Series B Financing
November 30, 2006
Merck & Co., Inc. to
Acquire Sirna Therapeutics, Inc.
October 30, 2006
VaxInnate Secures $40
Million Series C Financing
October 25, 2006
Barrier Therapeutics, Inc.
to Raise $25 Million in Registered Direct Offering
September 15, 2006
Artisan Pharma, Inc. Raises $39 Million in a Series A
Financing
September 2, 2006
New Leaf Venture Partners
Announces $12 Million Financing in Tioga Pharmaceuticals
January 9, 2006
New Leaf Venture Partners
Announces $8.5 Million Financing in TransOral Pharmaceuticals
October 28, 2005
New Leaf Venture Partners
Announces $3.5 Million Financing in Direct Flow Medical
September 7, 2005
New Leaf Venture Partners
Announces $8 Million Investment in Cerexa's $50 Million
Financing; Investment is First from NLV Partners' Recently
Announced Fund Dedicated to Healthcare Technologies
August 23, 2005
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